Resource Type

Journal Article 205

Conference Videos 7

Year

2024 1

2023 20

2022 27

2021 18

2020 16

2019 9

2018 7

2017 17

2016 8

2015 11

2014 5

2013 7

2012 8

2011 3

2010 10

2009 9

2008 7

2007 6

2006 3

2005 1

open ︾

Keywords

Antenna 2

Internet of Things (IoT) 2

MEMS 2

Microstructure 2

exploration and development 2

non-small cell lung cancer 2

numerical simulation 2

ultra-low emission 2

“ 1

-shaped value 1

1 000 MW nuclear power plant 1

2-dimensional interpolation 1

2′-O-methylation 1

4-nitrophenol 1

700& 1

700°C ultra-super-critical unit 1

N-nitrosamines 1

ADCP 1

AOD 1

open ︾

Search scope:

排序： Display mode:

Field measurement and analysis of asymmetric shallow buried twin tunnels with ultra small spacing

Wang Yunlong,Tan Zhongsheng,Chen Ying

Strategic Study of CAE 2012, Volume 14, Issue 11,   Pages 24-28

Abstract:

The ultra-small spacing tunnel of Jiaozhou Bay seabed tunnel in QingdaoThis result is different from the theoretical predictions and experimental results of most of the smallspacing symmetry tunnel.controlled, which provides useful reference for the design and construction of similar tunnels with smallspacing.

Keywords： tunnel     ultra-small spacing     asymmetric     shallow-buried     field measurement    

HTML PDF Collect

Review on the progress of ultra-precision machining technologies

Julong YUAN, Binghai LYU, Wei HANG, Qianfa DENG

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 2,   Pages 158-180 doi: 10.1007/s11465-017-0455-9

Abstract:

Ultra-precision machining technologies are the essential methods, to obtain the highest form accuracyThe conception, applications and history of ultra-precision machining are introduced in this article,and the developments of ultra-precision machining technologies, especially ultra-precision grinding,ultra-precision cutting and polishing are also reviewed.

Keywords： ultra-precision grinding     ultra-precision cutting     ultra-precision polishing     research status in China     development    

HTML PDF Collect

A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 108-111 doi: 10.1007/s11684-014-0344-0

Abstract: intra-abdominal recurrence from a previously resected gastrointestinal stromal tumour (GIST) of the smallIn this patient who presented with spontaneous rupture of a small intestinal GIST, the novel use of targeted

Keywords： gastrointestinal stromal tumour     hemoperitoneum     small bowel GIST     small bowel neoplasm     imatinib    

HTML PDF Collect

Gas marbles: ultra-long-lasting and ultra-robust bubbles formed by particle stabilization

Frontiers of Chemical Science and Engineering   Pages 1681-1687 doi: 10.1007/s11705-022-2180-0

Abstract: Bubbles and foams are ubiquitous in daily life and industrial processes. Studying their dynamic behaviors is of key importance for foam manufacturing processes in food packaging, cosmetics and pharmaceuticals. Bare bubbles are inherently fragile and transient; enhancing their robustness and shelf lives is an ongoing challenge. Their rupture can be attributed to liquid evaporation, thin film drainage and the nuclei of environmental dust. Inspired by particle-stabilized interfaces in Pickering emulsions, armored bubbles and liquid marble, bubbles are protected by an enclosed particle-entrapping liquid thin film, and the resultant soft object is termed gas marble. The gas marble exhibits mechanical strength orders of magnitude higher than that of soap bubbles when subjected to overpressure and underpressure, owing to the compact particle monolayer straddling the surface liquid film. By using a water-absorbent glycerol solution, the resulting gas marble can persist for 465 d in normal atmospheric settings. This particle-stabilizing approach not only has practical implications for foam manufacturing processes but also can inspire the new design and fabrication of functional biomaterials and biomedicines.

Keywords： bubble     particles     interfaces     armored bubble     liquid marble     gas marble     Pickering emulsion    

HTML PDF Collect

Properties of cement grout modified with ultra-fine slag

Sowmini GOPINATHAN, K B ANAND

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 1,   Pages 58-66 doi: 10.1007/s11709-017-0383-0

Abstract: The grout mixes of the present study contain cement, ultra-fine slag (UFS), super plasticizer and waterUltra-fine slag can be used as a supplementary cementitious material in cementitious grouts in order

Keywords： cement grout     ultra-fine slag     flowability     bleeding     viscosity    

HTML PDF Collect

Simulation and experimental improvement on a small-scale Stirling thermo-acoustic engine

Mao CHEN,Yonglin JU

Frontiers in Energy 2016, Volume 10, Issue 1,   Pages 37-45 doi: 10.1007/s11708-015-0390-6

Abstract: In this paper, the influence of the dimensions of the main parts of the small-scale Stirling thermo-acousticBased on the numerical simulation, a small-scale Stirling thermo-acoustic engine were constructed and

Keywords： thermo-acoustic Stirling engine     small-scale     simulation     experiment    

HTML PDF Collect

Discovery of small molecule degraders for modulating cell cycle

Frontiers of Medicine   Pages 823-854 doi: 10.1007/s11684-023-1027-5

Abstract: The cell cycle is a complex process that involves DNA replication, protein expression, and cell division. Dysregulation of the cell cycle is associated with various diseases. Cyclin-dependent kinases (CDKs) and their corresponding cyclins are major proteins that regulate the cell cycle. In contrast to inhibition, a new approach called proteolysis-targeting chimeras (PROTACs) and molecular glues can eliminate both enzymatic and scaffold functions of CDKs and cyclins, achieving targeted degradation. The field of PROTACs and molecular glues has developed rapidly in recent years. In this article, we aim to summarize the latest developments of CDKs and cyclin protein degraders. The selectivity, application, validation and the current state of each CDK degrader will be overviewed. Additionally, possible methods are discussed for the development of degraders for CDK members that still lack them. Overall, this article provides a comprehensive summary of the latest advancements in CDK and cyclin protein degraders, which will be helpful for researchers working on this topic.

Keywords： PROTAC     molecular glue     degrader     cell cycle     CDK     cyclin    

HTML PDF Collect

Fine-tuning cell organelle dynamics during mitosis by small GTPases

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 339-357 doi: 10.1007/s11684-022-0926-1

Abstract: Small GTPases belonging to the Ras superfamily regulate various cell organelles during division.Being the key regulators of membrane dynamics, the dysregulation of small GTPases is widely associatedRecent discoveries shed light on the molecular properties of small GTPases as sophisticated modulatorsThis review collects current knowledge on small GTPases in the regulation of cell organelles during mitosisand highlights the mediator role of small GTPase in transducing cell cycle signaling to organelle dynamics

Keywords： small GTPase     cell organelle     mitosis    

HTML PDF Collect

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 239-248 doi: 10.1007/s11684-018-0617-0

Abstract: In fact, several studies indicated that acute and chronic allograft rejection in small bowel transplantation

Keywords： gut microbiota     small bowel transplantation     acute rejection     chronic rejection     mucosal immunity     biomarker    

HTML PDF Collect

Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 157-171 doi: 10.1007/s11684-013-0272-4

Abstract:

Non-small-cell lung cancer (NSCLC) is the most common cause of premature death among the malignant

Keywords： non-small-cell lung cancer     molecular typing     individualized medicine     molecular-targeted therapy     gene expression    

HTML PDF Collect

Performance prediction of switched reluctance generator with time average and small signal models

Jyoti KOUJALAGI, B. UMAMAHESWARI, R. ARUMUGAM

Frontiers in Energy 2013, Volume 7, Issue 1,   Pages 56-68 doi: 10.1007/s11708-012-0216-8

Abstract: mathematical model and predicts the performance of switched reluctance generator with time average and smallFinally, to track control voltage and current wave shapes, a small signal model is designed.

Keywords： generator     reluctance     switching model     small signal model     time average model    

HTML PDF Collect

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 18-42 doi: 10.1007/s11684-022-0976-4

Abstract: With the improved understanding of driver mutations in non-small cell lung cancer (NSCLC), expanding

Keywords： non-small cell lung cancer     driver mutations     treatment strategy     resistant mechanism     immune-checkpoint    

HTML PDF Collect

Paternal environmental exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 176-184 doi: 10.1007/s11684-021-0885-y

Abstract: Recently, small noncoding RNAs (sncRNAs) in sperm have seemed crucial to this transmission due to their

Keywords： small noncoding RNAs     epigenetic inheritance     paternal intergenerational inherence     extracellular vesicles    

HTML PDF Collect

Special issue: Ultra-precision machining

Zhuangde JIANG,Dongming GUO

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 1,   Pages 1-2 doi: 10.1007/s11465-017-0445-y

HTML PDF Collect

Shear behavior of ultra-high-performance concrete beams prestressed with external carbon fiber-reinforced

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 6,   Pages 1426-1440 doi: 10.1007/s11709-021-0783-z

Abstract: The ultra-high-performance concrete (UHPC) and fiber-reinforced polymer (FRP) are well-accepted high-performance

Keywords： beam     external prestressing     ultra-high-performance concrete     fiber-reinforced polymers     shear behavior    

HTML PDF Collect

Title Author Date Type Operation

Field measurement and analysis of asymmetric shallow buried twin tunnels with ultra small spacing

Wang Yunlong,Tan Zhongsheng,Chen Ying

Journal Article

Review on the progress of ultra-precision machining technologies

Julong YUAN, Binghai LYU, Wei HANG, Qianfa DENG

Journal Article

A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum

Eric C.H. Lai,Kam Man Chung,Stephanie H.Y. Lau,Wan Yee Lau

Journal Article

Gas marbles: ultra-long-lasting and ultra-robust bubbles formed by particle stabilization

Journal Article

Properties of cement grout modified with ultra-fine slag

Sowmini GOPINATHAN, K B ANAND

Journal Article

Simulation and experimental improvement on a small-scale Stirling thermo-acoustic engine

Mao CHEN,Yonglin JU

Journal Article

Discovery of small molecule degraders for modulating cell cycle

Journal Article

Fine-tuning cell organelle dynamics during mitosis by small GTPases

Journal Article

Gut microbiota and its implications in small bowel transplantation

Chenyang Wang, Qiurong Li, Jieshou Li

Journal Article

Molecular classification of non-small-cell lung cancer: diagnosis, individualized treatment, and prognosis

Yue Yu, Jie He

Journal Article

Performance prediction of switched reluctance generator with time average and small signal models

Jyoti KOUJALAGI, B. UMAMAHESWARI, R. ARUMUGAM

Journal Article

Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future

Journal Article

Paternal environmental exposure-induced spermatozoal small noncoding RNA alteration meditates the intergenerational

Journal Article

Special issue: Ultra-precision machining

Zhuangde JIANG,Dongming GUO

Journal Article

Shear behavior of ultra-high-performance concrete beams prestressed with external carbon fiber-reinforced

Journal Article